tolerance

I’ve always had a really high tolerance for substances. All types. 

I guess that shrooms and MDMA get a pass but things like booze, weed, caffeine.. zero to a hundred in a matter of days. Cocaine I didn’t feel anything; big red flag and left it alone.

Then Abilify comes along and a low starter dose for children sends me totally loopy for a week.

I think it comes down to how these things work, and why I wanted to avoid stimulants. When I found out I had adhd I went straight to the host of a podcast who had just released a book; a researcher with the most current knowledge. I asked his take; leaky synapses.

So find a drug that can plug them. Easy. JD, candidate. I shortlisted 2 (Abilify, Wellbutrin) and went with top candidate first. When rejected I asked for secondary candidate but they couldn’t access so came full circle.

Anyway this med completely trashed me for a week. We are talking half-pill MDMA level if you were dropping mitsubishis back in the gatecrasher days. That’s where I’m sat now. Maybe quarter pill.

So yeah these substances I had a great tolerance for all threw more water at the sieve. Even MDMA.  But booze, weed, coke, meth, adhd medication… it’s all throwing water at a leaky receptacle. How I had to keep throwing that water. That booze. That exercise. That approval. That drug. Whatever. Until the Lagrange point rolls around or the defence mechanism kicks in.

So I guess that this is more evidence for both the hypothesis of leaky synapses and the clinical efficacy of the drug. 

And this might even be a way to chemically test for adhd. If someone doesn’t have leaky synapses, you wouldn’t expect the same response.

Good data.

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